Ⅰ. Diabetes:

We offer comprehensive research services for glucose metabolism and diabetes, including various glucose tolerance tests (GTT) and long-term efficacy assessments. We can perform oral GTT, intraperitoneal GTT in rats and mice, and intravenous GTT in rats to assess the impact of different routes of administration on blood glucose homeostasis. In addition, we offer urine glucose testing and long-term efficacy studies using db/db mice and other hyperglycemic models, as well as long-acting studies to evaluate improvements in insulin sensitivity, which can be used to assess the long-term therapeutic effects of candidate drugs on diabetes. Our experienced research team will provide you with high-quality data, detailed experimental reports, and professional scientific interpretations, providing strong support for your diabetes research.

1. Animal Models of Diabetes and Testing Parameters:

 

II. Acute Lung Injury

We offer comprehensive services for constructing and evaluating acute lung injury (ALI) models. ALI is a severe respiratory disease caused by a variety of direct or indirect factors. Its pathological features include damage to alveolar epithelial cells and capillary endothelial cells, leading to diffuse interstitial and alveolar edema, ultimately resulting in acute hypoxemic respiratory failure. We can construct a variety of ALI animal models according to your research needs, such as: lipopolysaccharide (LPS)-induced ALI model, mechanical ventilation-induced ALI model, acid aspiration-induced ALI model, and sepsis-induced ALI model. In addition, we also provide comprehensive testing services for ALI-related indicators, including but not limited to: lung histopathology (e.g., alveolar wall thickening, inflammatory cell infiltration, pulmonary edema, etc.), bronchoalveolar lavage fluid (BALF) analysis (e.g., protein concentration, cell count, cytokine levels, etc.), blood gas analysis, lung function testing, and detection of inflammatory factors and oxidative stress markers. Our experienced team is committed to providing high-quality data and detailed experimental reports, providing strong support for your ALI research.

Acute Lung Injury Models:

III. Anesthesia

We offer professional services for building anesthesia models and testing related parameters, covering a variety of anesthesia methods and animal types. We can establish various anesthesia models according to your specific research needs, including inhalation anesthesia, intravenous anesthesia, intramuscular injection anesthesia, and intraperitoneal injection anesthesia. We can perform anesthesia procedures on animals such as rats, mice, rabbits, dogs, pigs, and non-human primates. In addition, we also offer comprehensive monitoring of anesthesia depth and physiological indicators, including but not limited to: heart rate, respiratory rate, blood pressure, blood oxygen saturation, body temperature, electroencephalogram (EEG), and evoked potentials. Our experienced anesthesia team and advanced equipment will ensure animal welfare and the reliability of experimental data, providing high-quality technical support for your anesthesia-related research.

Anesthesia Models and Testing:

IV. Pruritus (Itch)

We offer comprehensive services for building and evaluating pruritus (itch) models, covering a variety of pruritogenic models, including compound-induced models (e.g., histamine, 5-hydroxytryptamine, capsaicin, etc.), allergic contact dermatitis models, atopic dermatitis models, and chronic pruritus models. We can ｓｅｌｅｃｔ appropriate animal models (e.g., mice, rats, guinea pigs, etc.) according to your specific research needs, and provide corresponding behavioral assessments (e.g., number of scratches, scratching time, etc.) and histological analysis services. In addition, we also provide itch-related indicator testing, such as inflammatory cytokines and neuropeptides. Our experienced research team will provide you with high-quality data and detailed experimental reports, providing strong support for your pruritus research.